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Cardiology Pharmaceuticals October 5, 2022

SGLT2i: A Universal Heart Failure Solution? October 5, 2022

Insights from the present study provide practical evidence to substantiate the initiation of SGLT2 inhibitors during or right after a hospitalization for heart failure.

Physician Reimbursements 20220930

Plaque AI’s Reimbursement Milestone 20220930

The small list of cardiac imaging AI solutions to earn Medicare reimbursements just got bigger, following CMS’ move to add an OPPS code for AI-based coronary plaque assessments. That represents a major milestone for Cleerly, who filed for this code and leads the plaque AI segment, and it marks another sign of progress for the business of imaging AI.

Cardiology Pharmaceuticals 20220928

Deprescribing Aspirin 20220928

For people on warfarin, discontinuing aspirin use may significantly reduce bleeding events without compromising thrombotic risks.

Surgeries & Interventions 20220923

Aggressive LDL Reduction Strategy 20220923

A new study shows aggressive in-hospital PCSK-9 therapy (plus statins) for heart attack patients would likely mean fewer deaths and cardiovascular events.

Surgeries & Interventions 20220921

Renal Denervation’s Comeback 20220921

While previous studies may have fallen short and more research might be needed, physicians and regulators can have renewed confidence that Medtronic’s Symplicity system and ReCor’s Paradise device lower blood pressure.

Preventive Cardiology 20220915

Is HFpEF an Exercise Deficiency Syndrome? 20220915

Thinking of HFpEF as an exercise deficiency syndrome will help physicians better understand the condition, recognize risk earlier, and most importantly, provide a clear path to prevention.

Cardiology Pharmaceuticals 20220914

Polypill’s Simplicity Advantage 20220914

A study in NEJM found that heart attack patients who took a “polypill” (a 3-part cocktail of aspirin, ramipril, and atorvastatin) had a lower risk of major CV events. But findings from the SECURE trial also left some docs scratching their heads.

Cardiovascular Disease Solutions 20220911

GRACE 3.0: Correcting the Default Male Risk 20220911

A Lancet-published study tackled the limitations of the GRACE 2.0 heart attack mortality risk score – namely, the systematic underestimation of mortality risk in female patients.

Surgeries & Interventions 20220902

Medtronic’s Defibrillation Innovation 20220902

A new era of implantable cardioverter-defibrillators (ICDs) may be on the horizon.

Surgeries & Interventions 20220831

PCI Fizzles in REVIVED Study 20220831

The highly anticipated REVIVED trial found that percutaneous coronary intervention (PCI) does not reduce all-cause mortality or heart failure hospitalization in patients with severe ventricular dysfunction. 

Guidelines 20220828

Statin Guidelines Spark Debate 20220828

The new USPSTF statin recommendations sparked debate last week, eliciting four editorials published the same day in the JAMA journal family. 

Cardiovascular Disease 20220824

Obesity Paradox Bias 20220824

New findings suggest it is worse to be normal weight than to have a BMI in the obese range. Does this track? One thought leader warns of collider bias—a subtype of selection bias—within the study.

Cardiac Imaging 20220821

Echo Clues: When to Suspect Amyloidosis 20220821

Routine echocardiographic parameters may prove to be “the key” to spotting cardiac amyloidosis in the presence of aortic stenosis. 

Cardiology Guidelines 20220817

Algorithm Aversion in HF Care 20220817

In this heart failure clinical trial, Yale researchers found that providing clinicians with 1-year mortality risk estimates did not improve patient outcomes nor influence decision-making. 

Cardiogenetics 20220812

For Genetic Tests, Size Matters  20220812

In contrast to typical practice, it appears that more comprehensive genetic panels produce meaningful insights that could guide physician decision-making. When it comes to testing for cardiomyopathies and arrhythmias, the added burden of uncertainty may be worth enduring.

Cardiovascular Disease 20220810

Heating Up: Two Heart Medications May Increase Risk 20220810

Antiplatelet medications and beta blockers can improve survival and quality of life for people with cardiovascular disease. But those protections may come with added risk on hot summer days.

Surgeries & Interventions 20220805

Physiological Pacing Movement Gains Momentum 20220805

Physiological pacing has witnessed tremendous growth in the last ten years, and new funding may provide the evidence physicians need to make it the heart failure standard of care.

Cardiology Pharmaceuticals 20220803

Alnylam’s Promising Heart Failure Treatment 20220803

Alnylam's Onpattro achieved the primary endpoint in its high-stakes APOLLO-B study for transthyretin amyloid cardiomyopathy.

Cardiogenetics 20220729

Why Men Die Earlier 20220729

A study published in Science found that the loss of the Y chromosome, which occurs naturally in many men as they age, can cause heart scarring and premature death.

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