Cardiac Wire #22

Aggressive LDL Reduction Strategy | Smart Stethoscopes

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Cardiology Pharmaceuticals September 14, 2022

Polypill’s Simplicity Advantage September 14, 2022

A study in NEJM found that heart attack patients who took a “polypill” (a 3-part cocktail of aspirin, ramipril, and atorvastatin) had a lower risk of major CV events. But findings from the SECURE trial also left some docs scratching their heads.

Cardiovascular Disease Solutions September 11, 2022

GRACE 3.0: Correcting the Default Male Risk September 11, 2022

A Lancet-published study tackled the limitations of the GRACE 2.0 heart attack mortality risk score – namely, the systematic underestimation of mortality risk in female patients.

Surgeries & Interventions September 2, 2022

Medtronic’s Defibrillation Innovation September 2, 2022

A new era of implantable cardioverter-defibrillators (ICDs) may be on the horizon.

Surgeries & Interventions August 31, 2022

PCI Fizzles in REVIVED Study August 31, 2022

The highly anticipated REVIVED trial found that percutaneous coronary intervention (PCI) does not reduce all-cause mortality or heart failure hospitalization in patients with severe ventricular dysfunction. 

Guidelines August 28, 2022

Statin Guidelines Spark Debate August 28, 2022

The new USPSTF statin recommendations sparked debate last week, eliciting four editorials published the same day in the JAMA journal family. 

Cardiovascular Disease August 24, 2022

Obesity Paradox Bias August 24, 2022

New findings suggest it is worse to be normal weight than to have a BMI in the obese range. Does this track? One thought leader warns of collider bias—a subtype of selection bias—within the study.

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-- The Cardiac Wire Team