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Cardiac Wire #381
HF Polypills, ACC’s Best Hospitals, and Cardiac Imaging News
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Artificial Intelligence July 2, 2026
DETECT AS II and the Importance of Assertive Notifications July 2, 2026
We already know that passive EHR alerts improve severe aortic stenosis management, but the DETECT AS II study now suggests a more forceful “opt-out” approach could substantially increase how many patients get timely valve replacement.
Heart Failure July 2, 2026
Uncertainty Lingers on VNS for HF After Shortened Study July 2, 2026
Freshly published data from LivaNova’s pivotal ANTHEM-HFrEF trial hinted that vagal nerve stimulation might help patients with HFrEF, but the company's early termination decision left some questions unanswered.
Structural Heart June 29, 2026
EARLY TAVR 5-Year Data Answer Some Questions, Raise Others June 29, 2026
Whether or not to intervene early in asymptomatic aortic stenosis was answered by EARLY TAVR in 2024, and new 5-year data presented at NYV 2026 now suggests that the benefit of early intervention is driven by reductions in death and stroke rather than just heart failure.
Cardiology Practices June 25, 2026
APPs are Growing in Compensation and Relevance in Cardiology June 25, 2026
Advanced practice providers have long been viewed as support staff in cardiology, but MedAxiom's new 2025 APP Compensation and Utilization Report suggests they've moved well beyond that role.
More Stories
Heart Failure June 22, 2026
Heart Failure GDMT Reduces Hospitalizations and Financial Burden June 22, 2026
The four-drug guidelines for heart failure with reduced ejection fraction are well established to cut hospitalizations and a new economic analysis in JAMA suggests that the hospital cost-savings more than cover the cost of the drugs themselves.
Surgeries & Interventions June 18, 2026
Ten Year TAVR Data and Why Valve Generations Matter June 18, 2026
TAVR has been among the default therapies for aortic stenosis patients for years now, but new 10-year data from the PARTNER 2A trial and the P2S3i Sapien 3 registry suggests that how long a valve will last depends heavily on the valve’s generation.
Cardiology Guidelines June 15, 2026
The CKM Guidelines Have Officially Arrived June 15, 2026
The AHA/ACC, in alliance with the ADA and ASN have officially recognized and released the first guidelines addressing cardiovascular-kidney-metabolic (CKM) syndrome as a real and important driver of cardiovascular disease.
Cardiovascular Disease June 11, 2026
Low Blood Pressure’s Alzheimer’s Link June 11, 2026
Hypertension has long been tied to cognitive decline, but new research in JAHA suggests it's actually hypotension that carries the strongest association with Alzheimer's disease.
Cardiology Practices June 8, 2026
Pay-for-Performance Doesn’t Pay Off in Results June 8, 2026
Pay-for-performance programs (a form of value-based care) are supposed to improve patient care, but a new JAMA study suggests that one hypertension control incentive might be making the numbers look better while actually increasing hospitalizations.
Population Health June 4, 2026
It’s Getting Hot in Here, So Watch Out for Your Heart June 4, 2026
America's cardiovascular burden from rising temperatures is set to nearly triple by 2050, with a new JAMA Cardiology study predicting thousands more CV deaths per year due to high-emissions and climate change.
Cardiology June 1, 2026
One Microplastic’s Way to Your Heart is Through the Gut June 1, 2026
Most microplastic research usually focuses on tissue build-up, but a new Circulation study suggests Bisphenol F (BPF) damages our heart muscle through an unexpected pathway in the gut.
Cardiology May 28, 2026
The 40 Best Cardiology Resources to Follow in 2026 May 28, 2026
Whether it’s debate about technology, therapy, or ethics, cardiologists are some of the most vocal and passionate members of the medical community, and their opinions can be found across X, LinkedIn, and beyond.
Heart Failure May 21, 2026
Inflammation’s Prevalence and Role in Heart Failure May 21, 2026
Heart failure inflammation might actually be an underrecognized therapeutic target, after results from the POSEIDON registry analysis found that systemic inflammation is present in nearly half of heart failure patients, regardless of ejection fraction.
Structural Heart May 18, 2026
Cardiac Wire’s State of The Transcatheter Valve May 18, 2026
It might feel like a transcatheter alphabet soup out there with all of the valve interventions that have come out in the last few years, but Cardiac Wire is here to help make sense of it all.
Structural Heart May 14, 2026
The Young TAVR Trend is Stabilizing May 14, 2026
Despite a TAVR popularity surge in recent years, a Vizient registry analysis suggests the procedure’s prevalence has stabilized in patients under 65, but there’s still significant debate on whether the young patient TAVR rate is appropriate.
Cardiovascular Disease May 11, 2026
BP Lowering Still Decreases CVD Risk Even in CKD May 11, 2026
Data from a new Lancet study suggests that patients with chronic kidney disease (CKD) might get similar cardiovascular protection from blood pressure drugs as the general population, giving physicians some certainty about how to approach BP in these patients.
Cardiology Pharmaceuticals May 7, 2026
Aficamten, ACACIA-HCM, and the Road to the First nHCM Drug May 7, 2026
The question of how to treat non-obstructive hypertrophic cardiomyopathy has long perplexed researchers and pharmaceutical developers alike, but topline results from Cytokinetics’ Phase 3 ACACIA-HCM trial suggest MYQORZO (aficamten) could be the answer.
Cardiovascular Disease May 4, 2026
The True Cause of Sudden Cardiac Death May 4, 2026
It’s not often that a pair of studies completely challenges our assumptions in cardiology, but new data presented at HRS 2026 suggests myocardial infarction might not be […]
Cardiology April 30, 2026
Cardiac Wire’s Top Six of HRS 2026 April 30, 2026
The Heart Rhythm Society's Annual Meeting for 2026 electrified Chicago with talks of the latest EP tech, rhythm management debates, and insights into where remote patient monitoring is headed. Here are Cardiac Wire’s top-six takeaways from electrophysiology’s biggest weekend of the year.
Cardiology Testing April 27, 2026
Better hs-cTnT Assays, Lower Healthcare Burden April 27, 2026
Cardiac troponin assays might be the gold standard for diagnosing a heart attack in the ER, but a new JAMA study suggests the latest generation of tests could significantly reduce false positives and ultimately, health system burden.
Patient Engagement April 23, 2026
Calcium Supplements May Have CV Risks April 23, 2026
While the verdict is still out on whether or not calcium supplements support bone health, new research in JAHA suggests they’re not good for your heart.
Surgeries & Interventions April 20, 2026
A Look Into Real-World TTVR Results April 20, 2026
We’re finally starting to get some real-world data on treating tricuspid regurgitation with transcatheter tricuspid valve replacement (TTVR) and a new TVT registry study suggests TTVR outcomes are even better than previously thought.