Cardiovascular Disease

The Impact of Physical Activity Before and After CV Events

A long-term analysis of the CARDIA study revealed that moderate-to-vigorous physical activity steadily declines from young adulthood through midlife, but patients destined to develop cardiovascular disease experience rapid activity decreases more than a decade before their first event.

  • Studies have shown that moderate-to-vigorous physical activity (MVPA) is critical for both preventing and managing cardiovascular disease.
  • To help stave off CVD, guidelines recommend 150 minutes per week of MVPA.
  • However, previous research focused on short-term activity patterns rather than lifelong impact on cardiac events.

Collecting data over 37 years, researchers tracked ~3k participants from young adulthood to middle age and paired each individual with a matched control partner, finding that…

  • Patients who eventually developed CVD, began decreasing their physical activity levels roughly 12 years before their cardiac events.
  • Activity decline accelerated sharply within 2 years before their first cardiovascular event.
  • Post-CVD, patients remained 78% more likely to maintain low activity levels compared to matched controls.
  • Heart failure patients showed the steepest pre-event declines and consistently low post-event activity.

Researchers also identified striking demographic disparities that persisted throughout the entire study, even after adjusting for pre-CVD activity levels…

  • Black women consistently reported the lowest MVPA levels across all age groups.
  • Black women also faced the highest risk of low post-CVD activity (OR: 4.52).
  • Black men experienced more sustained activity decline compared to other groups.

The Takeaway

This 37-year study reveals that CVD casts a long shadow, with physical activity decline beginning more than a decade before clinical events manifest. Even more sobering is the fact that post-CV-event activity gaps suggest traditional cardiac rehabilitation may not be enough for long-term recovery. In other words, don’t wait till it’s broken to fix it.

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