Cardiology Pharmaceuticals
November 24, 2025
Winrevair Shows Early HFpEF Win in CADENCE November 24, 2025
Winrevair (sotatercept-csrk) might become Merck’s next blockbuster after positive Phase 2 results from the CADENCE study showed it led to significant improvements in pulmonary blood flow in patients with precapillary pulmonary hypertension due to HFpEF. Focused on exploring Winrevair’s HF impact, the Phase 2 CADENCE study enrolled 164 adults with PAH caused by HFpEF, comparing […]
Structural Heart
November 20, 2025
Meril’s Myval Makes its Mark With LANDMARK November 20, 2025
The TAVR race might be closer to having another competitor in North America, after the LANDMARK trial’s one-year results suggest that Meril’s Myval THV series achieved comparable clinical efficacy to both Edwards’ Sapien and Medtronic’s Evolut AVR systems. The LANDMARK trial enrolled 768 patients with symptomatic severe aortic stenosis at 31 sites across 16 countries, […]
Atrial Fibrillation
November 17, 2025
CLOSURE-AF Results Question Just How Good LAAO Is November 17, 2025
There’s been some serious debate over the last few years about whether or not left atrial appendage occlusion is actually the best stroke prevention option for high-risk AFib patients, and the latest results from the CLOSURE-AF trial suggest it might not be as effective as previously thought. To bring closure to the LAAO debate, CLOSURE-AF […]