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Heart Failure November 6, 2025
PREVENT-TAHA8 Supports Stem Cells for Post-MI HF November 6, 2025
Stem cell therapy for post-MI heart failure might deserve a second look, after the PREVENT-TAHA8 trial demonstrated that mesenchymal stem cell infusion within days of STEMI significantly reduced 3-year HF incidence. Based in Iran, the PREVENT-TAHA8 trial, randomized 396 patients following LAD STEMI with LVEF <40%, to receive either an intracoronary mesenchymal stem cell infusion […]
Structural Heart November 3, 2025
Abbott’s Tendyne TMVR System Works Even in the Sickest MR Patients November 3, 2025
New research presented at TCT 2025 suggests that Abbott’s FDA-approved Tendyne TMVR system leads to significantly better health outcomes in patients with severe mitral annular calcification who were previously considered untreatable. The SUMMIT-MAC trial enrolled 103 patients with severe MAC and found that the challenging patient population showed strong outcomes despite extreme pathology… However, patients […]
Cardiology October 30, 2025
The Top Trends of TCT 2025 October 30, 2025
This year marked the 37th Annual Transcatheter Cardiovascular Therapeutics conference, and while the core of the conference is still catheter-based heart therapies, this year’s research studies and device demonstrations made it clearer than ever that cardiac medtech continues to push the boundaries of what can be done with a catheter. Structural Heart is King – […]
Cardiovascular Disease October 27, 2025
Genetic Risk Scores Improve CAD Detection October 27, 2025
Coronary artery disease risk assessment might soon rely on genetic testing, following a UK Biobank analysis that suggests adding a CAD multi-gene risk score to conventional biomarkers significantly improves disease prediction and patient identification. Examining genetic profiles, researchers followed 353k UK Biobank participants without baseline CAD for 11 years on average, and compared the predictive […]
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Hypertension October 23, 2025
Intensive BP Lowering Doesn’t Hurt Patient QoL October 23, 2025
Intensive blood pressure lowering might enhance patient wellbeing, after the deeper analysis of the ESPRIT trial demonstrated that lowering systolic BP to <120 mmHg leads to modest but significant improvements in health-related quality of life. To fill in these gaps, the ESPRIT QoL analysis examined 5.4k intensive treatment and 5.4k standard treatment participants over a […]
Heart Failure October 20, 2025
Don’t Blame Your Heart for Heart Failure October 20, 2025
Perhaps the biggest cardiology story of the year, an entire issue of JACC now hypothesizes that heart failure with preserved ejection fraction (HFpEF) might actually be caused by visceral fat tissue that triggers cardiac weakening through adipokine signaling. The new unifying adiposity framework now proposes that visceral fat expansion causes secretion of an altered adipokine […]
Cardiology Business October 16, 2025
MedAxiom Report: Cardiologist Compensation Soars, Patient Access Struggles October 16, 2025
Good news and bad news from MedAxiom’s latest cardiology compensation survey. The good news? Cardiologist median compensation reached new record highs last year. The bad news? Patient access deteriorated while the number of patients physicians had to manage swelled. The 2025 survey findings aggregated data across cardiology, cardiac surgery, and vascular surgery specialties, examining compensation […]
Heart Failure October 13, 2025
Specialist Care Can Improve HF Outcomes Across the Board October 13, 2025
A recent study out of the U.K. suggests that multidisciplinary team management could significantly reduce death or rehospitalization risk for HF patients across the LVEF spectrum. Based in a single U.K. county, the Buckinghamshire analysis examined 2.1k patients hospitalized for acute heart failure who received either specialist care or standard care over a 618-day follow-up […]
Cardiology Testing October 9, 2025
Screening For Lp(a) is Still Too Uncommon October 9, 2025
A recent JACC analysis of the Epic Cosmos database suggests lipoprotein(a) screening is still one of cardiology’s most neglected risk assessment tools, representing a serious gap in the way we evaluate patients’ CVD risk. To learn more about Lp(a) testing trends, researchers searched for Lp(a) screening patterns in the Epic Cosmos database from 2015-2024 across […]
Cardiogenetics October 6, 2025
Secondary Cardiomyopathy Isn’t so Secondary After All October 6, 2025
Secondary cardiomyopathies might not be caused by environmental factors after all, after a massive four-biobank study found that their development is a lot more dependent on which combination of genetic risks you already have. The multi-biobank genetic analysis examined nearly 1.3M individuals identifying 3.4k people with secondary cardiomyopathies (70 PPCM, 2,281 ACM, 1,063 CCM). Upon […]
Heart Failure October 2, 2025
Where HF is Headed – Takeaways from HFSA 2025 October 2, 2025
Cardiac Wire attended its first ever Heart Failure Society of America meeting this year, exploring everything from the latest pharmaceutical advancements to the complex relationship between cardio-renal health and beyond. Here are some of the big takeaways from HFSA 2025. Heart Failure Comes in Many Forms: While the gold-standard for diagnosing heart failure is still […]
Cardiology September 29, 2025
CVD: A Bigger Global Health Problem Than We Realize September 29, 2025
The latest Global Burden of Disease study revealed that cardiovascular disease is a bigger part of the global health battle than previously thought, underscoring the impact of CVD on population-level health despite medical advances. Presented at the UN General Assembly 2025, the Global Burden of Disease study looked at cardiovascular disease patterns across regions and […]
Cardiovascular Disease Solutions September 26, 2025
Breaking Barriers in Coronary Care: Abbott’s New IVL System Targets Severe Calcification September 26, 2025
By: Jennifer Jones-McMeans, PhD , Divisional Vice President of Global Clinical Affairs at AbbottSponsored by Abbott Severe calcification is one of the complex challenges faced by interventional cardiologists. Intravascular Lithotripsy (IVL) is emerging as a promising treatment option for Coronary Artery Disease (CAD). Traditional therapies for calcified arterial blockages include cutting balloons and atherectomy. However, […]
Cholesterol Reduction September 25, 2025
Meds-to-Beds Improve PCSK9 Inhibitor Access and Efficacy September 25, 2025
PCSK9 inhibitors might finally reach their clinical potential in the patients who need them most, after the ELL-ASCVD study demonstrated that a Meds-to-Beds program delivering these medications before hospital discharge significantly improved patient uptake. The ELL-ASCVD program enrolled 72 patients immediately following their revascularization procedures, with 69% post-PCI, 18% post-CABG, and 13% post-peripheral interventions, finding […]
Cardiovascular Disease September 22, 2025
OCTOPUS: What Really Causes MI in Younger Patients September 22, 2025
Young heart attack patients might actually be a completely different disease population than previously understood, after the OCTOPUS registry analysis revealed that the causes of early MI and the people who get them aren’t what’s expected. The OCTOPUS registry analyzed 4k cardiac events between 2003-2018, using medical record linkage to classify MI etiologies in patients […]
Cardiology Practices September 18, 2025
What Cardiologists Say vs. What Patients Hear September 18, 2025
Cardiovascular risk communication might be failing patients when they need it most, after the HARIPA study revealed significant disconnects between patient and physician perceptions of future cardiovascular risk and procedural complications. The HARIPA study surveyed cardiology inpatients and their physicians from October 2022 to March 2023, using structured questionnaires to assess risk perception and communication […]
Digital Health September 15, 2025
TRICORDER Shows Potential of AI Stethoscopes September 15, 2025
Results from the massive TRICORDER study suggest Eko Health’s AI-powered stethoscopes could change the way primary care providers perform cardiac screening, potentially catching thousands more patients for cardiologists to treat. The TRICORDER study results encompassed 205 NHS GP practices over 12 months, with nearly 1,000 providers performing more than 12.8k AI-stethoscope exams in routine care […]
Cardiology September 11, 2025
Cardiac Wire’s ASE 2025 Takeaways September 11, 2025
The American Society of Echocardiography left an echo this year in Music City as it celebrated its 50th year. Among the studies and products unveiled at ASE 2025, here are Cardiac Wire’s top five takeaways from the meeting. Premium Echo Has Found its Stride – Although most typically think of ultrasound as a lower cost […]
Cardiology Business September 8, 2025
Edwards Acquires Vectorious, Bolsters HF Portfolio September 8, 2025
Edwards Lifesciences took another step towards becoming a major player in remote heart failure monitoring, after fully acquiring Israeli startup Vectorious Medical Technologies for $497M in cash. Vectorious’ monitoring device is known as the V-LAP system and it uses a minimally invasive approach to achieve continuous HF monitoring through a tiny, battery-free sensor implanted in […]
Cardiology Pharmaceuticals September 4, 2025
The Differences in HCM, Results from ODYSSEY and MAPLE September 4, 2025
In a big step towards better hypertrophic cardiomyopathy treatments, two separate studies presented at ESC suggest cardiac myosin inhibitors’ efficacy depends critically on whether patients have the obstructive or nonobstructive form of the disease. Two different trials presented insightful outcomes at ESC 2025, with MAPLE-HCM testing aficamten versus metoprolol in obstructive HCM patients, and ODYSSEY-HCM […]
Cardiology August 28, 2025
Cardiologists, Practice What You Preach! August 28, 2025
Cardiologists might be struggling with the same lifestyle challenges they counsel patients about, as a national survey of ACC members revealed significant gaps between what physicians’ recommend and how they act. The ACC CardioSurve study surveyed 166 U.S. cardiologists about their training in lifestyle medicine and clinical recommendations across all six lifestyle pillars, revealing some […]
Obesity Care August 25, 2025
GLP-1s Work, But Not for Free August 25, 2025
Real-world semaglutide (Wegovy) patients might be experiencing a healthcare cost paradox, after a recent analysis in JAMA showed that GLP-1s successfully reduce weight and improve cardiovascular risk factors, but lead to increased patient healthcare expenditures in the short term. The real-world analysis examined 23.5k adults prescribed semaglutide between January 2018 and January 2025 across two […]