Heart Failure
December 4, 2025
How the Causes of Heart Failure Have Changed Over 35 Years December 4, 2025
A new NHANES analysis adds to the idea that heart failure might be more of a metabolic disease than just a cardiac problem, revealing that HF prevalence has remained constant over the last 35 years as ischemic causes decreased and metabolic factors increased. Examining over 30 years of data, the study analyzed 83.5k ambulatory participants […]
Cardiology Testing
December 1, 2025
Risk Equations Fail Younger MI Patients December 1, 2025
Prevention guidelines might be failing younger patients, after a new JACC Advances analysis of first-MI patients under 65 revealed that over half would not have qualified for statins just two days before their cardiac event based on their ASCVD Risk Estimator Plus and PREVENT equations scores. Assessing these equations’ applicability to younger people, researchers examined […]
Cardiology Pharmaceuticals
November 24, 2025
Winrevair Shows Early HFpEF Win in CADENCE November 24, 2025
Winrevair (sotatercept-csrk) might become Merck’s next blockbuster after positive Phase 2 results from the CADENCE study showed it led to significant improvements in pulmonary blood flow in patients with precapillary pulmonary hypertension due to HFpEF. Focused on exploring Winrevair’s HF impact, the Phase 2 CADENCE study enrolled 164 adults with PAH caused by HFpEF, comparing […]
